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Cyclophilin D binds to the acidic C-terminus region of α-Synuclein and affects its aggregation characteristics

Cyclophilin D (CypD) is a peptidyl-prolyl isomerase expressed in the nucleus and transported into the mitochondria where it is best associated with the regulation of the mitochondrial permeability transition pore (MPTP). There are, however, other possible roles of CypD in the mitochondria which may...

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Detalles Bibliográficos
Autores principales: Torpey, James, Madine, Jillian, Wood, Amy, Lian, Lu-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311461/
https://www.ncbi.nlm.nih.gov/pubmed/32576835
http://dx.doi.org/10.1038/s41598-020-66200-9