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Cyclophilin D binds to the acidic C-terminus region of α-Synuclein and affects its aggregation characteristics
Cyclophilin D (CypD) is a peptidyl-prolyl isomerase expressed in the nucleus and transported into the mitochondria where it is best associated with the regulation of the mitochondrial permeability transition pore (MPTP). There are, however, other possible roles of CypD in the mitochondria which may...
Autores principales: | Torpey, James, Madine, Jillian, Wood, Amy, Lian, Lu-Yun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311461/ https://www.ncbi.nlm.nih.gov/pubmed/32576835 http://dx.doi.org/10.1038/s41598-020-66200-9 |
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