Cargando…
The iron–sulphur cluster in human DNA2 is required for all biochemical activities of DNA2
The nuclease/helicase DNA2 plays important roles in DNA replication, repair and processing of stalled replication forks. DNA2 contains an iron-sulphur (FeS) cluster, conserved in eukaryotes and in a related bacterial nuclease. FeS clusters in DNA maintenance proteins are required for structural inte...
Autores principales: | Mariotti, Laura, Wild, Sebastian, Brunoldi, Giulia, Piceni, Alessandra, Ceppi, Ilaria, Kummer, Sandra, Lutz, Richard E., Cejka, Petr, Gari, Kerstin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311471/ https://www.ncbi.nlm.nih.gov/pubmed/32576938 http://dx.doi.org/10.1038/s42003-020-1048-4 |
Ejemplares similares
-
Human DNA polymerase delta requires an iron–sulfur cluster for high-fidelity DNA synthesis
por: Jozwiakowski, Stanislaw K., et al.
Publicado: (2019) -
The internal region of CtIP negatively regulates DNA end resection
por: Howard, Sean Michael, et al.
Publicado: (2020) -
The iron–sulfur helicase DDX11 promotes the generation of single-stranded DNA for CHK1 activation
por: Simon, Anna K, et al.
Publicado: (2020) -
PLK1 regulates CtIP and DNA2 interplay in long-range DNA end resection
por: Ceppi, Ilaria, et al.
Publicado: (2023) -
The motor activity of DNA2 functions as an ssDNA translocase to promote DNA end resection
por: Levikova, Maryna, et al.
Publicado: (2017)