Widespread transcript shortening through alternative polyadenylation in secretory cell differentiation

Most eukaryotic genes produce alternative polyadenylation (APA) isoforms. Here we report that, unlike previously characterized cell lineages, differentiation of syncytiotrophoblast (SCT), a cell type critical for hormone production and secretion during pregnancy, elicits widespread transcript shorte...

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Detalles Bibliográficos
Autores principales: Cheng, Larry C., Zheng, Dinghai, Baljinnyam, Erdene, Sun, Fangzheng, Ogami, Koichi, Yeung, Percy Luk, Hoque, Mainul, Lu, Chi-Wei, Manley, James L., Tian, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311474/
https://www.ncbi.nlm.nih.gov/pubmed/32576858
http://dx.doi.org/10.1038/s41467-020-16959-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311474/
https://www.ncbi.nlm.nih.gov/pubmed/32576858
http://dx.doi.org/10.1038/s41467-020-16959-2

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