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Synergistic stabilization by nitrosoglutathione-induced thiol modifications in the stromal interaction molecule-2 luminal domain suppresses basal and store operated calcium entry
Stromal interaction molecule−1 and −2 (STIM1/2) are endoplasmic reticulum (ER) membrane-inserted calcium (Ca(2+)) sensing proteins that, together with Orai1-composed Ca(2+) channels on the plasma membrane (PM), regulate intracellular Ca(2+) levels. Recent evidence suggests that S-nitrosylation of th...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311479/ https://www.ncbi.nlm.nih.gov/pubmed/32576932 http://dx.doi.org/10.1038/s41598-020-66961-3 |