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High expression of spliced X-Box Binding Protein 1 in lung tumors is associated with cancer aggressiveness and epithelial-to-mesenchymal transition

Proteostasis imbalance is emerging as a major hallmark of cancer, driving tumor growth and aggressiveness. Endoplasmic Reticulum (ER) stress has been documented in most major cancers, and the ability to tolerate persistent ER stress through an effective unfolded protein response enhances cancer cell...

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Detalles Bibliográficos
Autores principales: Tavernier, Quentin, Legras, Antoine, Didelot, Audrey, Normand, Corinne, Gibault, Laure, Badoual, Cécile, Le Pimpec-Barthes, Françoise, Puig, Pierre Laurent, Blons, Hélène, Pallet, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311525/
https://www.ncbi.nlm.nih.gov/pubmed/32576923
http://dx.doi.org/10.1038/s41598-020-67243-8