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The mutREAD method detects mutational signatures from low quantities of cancer DNA

Mutational processes acting on cancer genomes can be traced by investigating mutational signatures. Because high sequencing costs limit current studies to small numbers of good-quality samples, we propose a robust, cost- and time-effective method, called mutREAD, to detect mutational signatures from...

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Detalles Bibliográficos
Autores principales: Perner, Juliane, Abbas, Sujath, Nowicki-Osuch, Karol, Devonshire, Ginny, Eldridge, Matthew D., Tavaré, Simon, Fitzgerald, Rebecca C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311535/
https://www.ncbi.nlm.nih.gov/pubmed/32576827
http://dx.doi.org/10.1038/s41467-020-16974-3