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FACS-Based Functional Protein Screening via Microfluidic Co-encapsulation of Yeast Secretor and Mammalian Reporter Cells
In this study, we present a straightforward approach for functional cell-based screening by co-encapsulation of secretor yeast cells and reporter mammalian cells in millions of individual agarose-containing microdroplets. Our system is compatible with ultra-high-throughput selection utilizing standa...
Autores principales: | Yanakieva, Desislava, Elter, Adrian, Bratsch, Jens, Friedrich, Karlheinz, Becker, Stefan, Kolmar, Harald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311539/ https://www.ncbi.nlm.nih.gov/pubmed/32576855 http://dx.doi.org/10.1038/s41598-020-66927-5 |
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