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Mesenchymal Stromal Cell Bioreactor for Ex Vivo Reprogramming of Human Immune Cells

Bone marrow mesenchymal stromal cells (MSCs) have been studied for decades as potent immunomodulators. Clinically, they have shown some promise but with limited success. Here, we report the ability of a scalable hollow fiber bioreactor to effectively maintain ideal MSC function as a single populatio...

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Detalles Bibliográficos
Autores principales: Allen, Ashley, Vaninov, Natalie, Li, Matthew, Nguyen, Sunny, Igo, Peter, Tilles, Arno W., O’Rourke, Brian, Miller, Brian L. K., Parekkadan, Biju, Barcia, Rita N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311545/
https://www.ncbi.nlm.nih.gov/pubmed/32576889
http://dx.doi.org/10.1038/s41598-020-67039-w