Chaetocin Abrogates the Self-Renewal of Bladder Cancer Stem Cells via the Suppression of the KMT1A–GATA3–STAT3 Circuit

Bladder cancer stem cells (BCSCs) have the abilities of self-renewal, differentiation, and metastasis; confer drug resistance; and exhibit high tumorigenicity. We previously identified that the KMT1A–GATA3–STAT3 axis drives the self-renewal of BCSCs. However, the therapeutic effect of targeting KMT1...

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Detalles Bibliográficos
Autores principales: Yang, Zhao, Wang, Haifeng, Zhang, Nan, Xing, Tianying, Zhang, Wei, Wang, Guoqing, Li, Chong, Yu, Changyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311639/
https://www.ncbi.nlm.nih.gov/pubmed/32626701
http://dx.doi.org/10.3389/fcell.2020.00424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311639/
https://www.ncbi.nlm.nih.gov/pubmed/32626701
http://dx.doi.org/10.3389/fcell.2020.00424

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