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Germline and Somatic Pharmacogenomics to Refine Rectal Cancer Patients Selection for Neo-Adjuvant Chemoradiotherapy

Neoadjuvant chemoradiotherapy (nCRT) followed by radical surgery is the standard of care for patients with Locally Advanced Rectal Cancer (LARC). Current selection for nCRT is based on clinical criteria regardless of any molecular marker. Pharmacogenomics may be a useful strategy to personalize and...

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Detalles Bibliográficos
Autores principales: De Mattia, Elena, Roncato, Rossana, Palazzari, Elisa, Toffoli, Giuseppe, Cecchin, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311751/
https://www.ncbi.nlm.nih.gov/pubmed/32625092
http://dx.doi.org/10.3389/fphar.2020.00897