IgG4 Autoantibodies Attenuate Systemic Lupus Erythematosus Progression by Suppressing Complement Consumption and Inflammatory Cytokine Production

Pathogenic autoantibodies can cause inflammation and tissue injury in systemic lupus erythematosus (SLE). Although IgG4 is considered non-inflammatory owing to the unique structure of its hinge region, the role of IgG4 autoantibodies in SLE remains largely unknown. The titers of serum anti-nuclear-I...

Descripción completa

Detalles Bibliográficos
Autores principales: Pan, Qingjun, Xiao, Haiyan, Shi, Lei, He, Yiming, Cai, Jun, Wu, Jing, Li, Aifen, Ye, Lin, Yang, Chen, Liu, Hua-feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311789/
https://www.ncbi.nlm.nih.gov/pubmed/32625200
http://dx.doi.org/10.3389/fimmu.2020.01047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311789/
https://www.ncbi.nlm.nih.gov/pubmed/32625200
http://dx.doi.org/10.3389/fimmu.2020.01047

Ejemplares similares