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LRRK2 and α-Synuclein: Distinct or Synergistic Players in Parkinson’s Disease?

Parkinson’s disease (PD) is the most common neurodegenerative movement disorder, characterized by prominent degeneration of dopaminergic neurons in the substantia nigra and aggregation of the protein α-synuclein within intraneuronal inclusions known as Lewy bodies. Ninety percent of PD cases are idi...

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Detalles Bibliográficos
Autores principales: O’Hara, Darren M., Pawar, Grishma, Kalia, Suneil K., Kalia, Lorraine V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311858/
https://www.ncbi.nlm.nih.gov/pubmed/32625052
http://dx.doi.org/10.3389/fnins.2020.00577