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Recombinant SARS-CoV-2 spike S1-Fc fusion protein induced high levels of neutralizing responses in nonhuman primates

The COVID-19 outbreak has become a global pandemic responsible for over 2,000,000 confirmed cases and over 126,000 deaths worldwide. In this study, we examined the immunogenicity of CHO-expressed recombinant SARS-CoV-2 S1-Fc fusion protein in mice, rabbits, and monkeys as a potential candidate for a...

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Detalles Bibliográficos
Autores principales: Ren, Wenlin, Sun, Hunter, Gao, George F., Chen, Jianxin, Sun, Sean, Zhao, Rongqing, Gao, Guang, Hu, Yalin, Zhao, Gan, Chen, Yuxin, Jin, Xia, Fang, Feng, Chen, Jinggong, Wang, Qi, Gong, Sitao, Gao, Wen, Sun, Yufei, Su, Junchi, He, Ailiang, Cheng, Xin, Li, Min, Xia, Chenxi, Li, Maohua, Sun, Le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311893/
https://www.ncbi.nlm.nih.gov/pubmed/32651113
http://dx.doi.org/10.1016/j.vaccine.2020.06.066