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Recombinant SARS-CoV-2 spike S1-Fc fusion protein induced high levels of neutralizing responses in nonhuman primates
The COVID-19 outbreak has become a global pandemic responsible for over 2,000,000 confirmed cases and over 126,000 deaths worldwide. In this study, we examined the immunogenicity of CHO-expressed recombinant SARS-CoV-2 S1-Fc fusion protein in mice, rabbits, and monkeys as a potential candidate for a...
Autores principales: | Ren, Wenlin, Sun, Hunter, Gao, George F., Chen, Jianxin, Sun, Sean, Zhao, Rongqing, Gao, Guang, Hu, Yalin, Zhao, Gan, Chen, Yuxin, Jin, Xia, Fang, Feng, Chen, Jinggong, Wang, Qi, Gong, Sitao, Gao, Wen, Sun, Yufei, Su, Junchi, He, Ailiang, Cheng, Xin, Li, Min, Xia, Chenxi, Li, Maohua, Sun, Le |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311893/ https://www.ncbi.nlm.nih.gov/pubmed/32651113 http://dx.doi.org/10.1016/j.vaccine.2020.06.066 |
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