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Embryonic Program Activated during Blast Crisis of Chronic Myelogenous Leukemia (CML) Implicates a TCF7L2 and MYC Cooperative Chromatin Binding

Chronic myeloid leukemia (CML) is characterized by an inherent genetic instability, which contributes to the progression of the disease towards an accelerated phase (AP) and blast crisis (BC). Several cytogenetic and genomic alterations have been reported in the progression towards BC, but the preci...

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Detalles Bibliográficos
Autores principales: Desterke, Christophe, Hugues, Patricia, Hwang, Jin Wook, Bennaceur-Griscelli, Annelise, Turhan, Ali G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312032/
https://www.ncbi.nlm.nih.gov/pubmed/32517078
http://dx.doi.org/10.3390/ijms21114057