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N2A Titin: Signaling Hub and Mechanical Switch in Skeletal Muscle

Since its belated discovery, our understanding of the giant protein titin has grown exponentially from its humble beginning as a sarcomeric scaffold to recent recognition of its critical mechanical and signaling functions in active muscle. One uniquely useful model to unravel titin’s functions, musc...

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Detalles Bibliográficos
Autores principales: Nishikawa, Kiisa, Lindstedt, Stan L., Hessel, Anthony, Mishra, Dhruv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312179/
https://www.ncbi.nlm.nih.gov/pubmed/32492876
http://dx.doi.org/10.3390/ijms21113974