Norepinephrine Inhibits the Proliferation of Human Bone Marrow-Derived Mesenchymal Stem Cells via β2-Adrenoceptor-Mediated ERK1/2 and PKA Phosphorylation

Bone marrow-derived mesenchymal stem cells (BMSCs) represent an alternative to chondrocytes to support cartilage regeneration in osteoarthritis (OA). The sympathetic neurotransmitter norepinephrine (NE) has been shown to inhibit their chondrogenic potential; however, their proliferation capacity und...

Descripción completa

Detalles Bibliográficos
Autores principales: Hedderich, Jessica, El Bagdadi, Karima, Angele, Peter, Grässel, Susanne, Meurer, Andrea, Straub, Rainer H., Zaucke, Frank, Jenei-Lanzl, Zsuzsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312191/
https://www.ncbi.nlm.nih.gov/pubmed/32486305
http://dx.doi.org/10.3390/ijms21113924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312191/
https://www.ncbi.nlm.nih.gov/pubmed/32486305
http://dx.doi.org/10.3390/ijms21113924

Ejemplares similares