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Human PSC-Derived Hepatocytes Express Low Levels of Viral Pathogen Recognition Receptors, but Are Capable of Mounting an Effective Innate Immune Response

Hepatocytes are key players in the innate immune response to liver pathogens but are challenging to study because of inaccessibility and a short half-life. Recent advances in in vitro differentiation of hepatocyte-like cells (HLCs) facilitated studies of hepatocyte–pathogen interactions. Here, we ai...

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Detalles Bibliográficos
Autores principales: Fischer, Lena, Lucendo-Villarin, Baltasar, Hay, David C., O’Farrelly, Cliona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312201/
https://www.ncbi.nlm.nih.gov/pubmed/32481600
http://dx.doi.org/10.3390/ijms21113831