In Vitro Effects of Ligand Bias on Primate Mu Opioid Receptor Downstream Signaling

Interest has emerged in biased agonists at the mu opioid receptor (MOR) as a possible means for maintaining potent analgesis with reduced side effect profiles. While approaches measuring in vitro biased agonism are used in the development of these compounds, their therapeutic utility will ultimately...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao, Hutchins, Shaurita D., Blough, Bruce E., Vallender, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312292/
https://www.ncbi.nlm.nih.gov/pubmed/32503269
http://dx.doi.org/10.3390/ijms21113999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312292/
https://www.ncbi.nlm.nih.gov/pubmed/32503269
http://dx.doi.org/10.3390/ijms21113999

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