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In Vitro Effects of Ligand Bias on Primate Mu Opioid Receptor Downstream Signaling
Interest has emerged in biased agonists at the mu opioid receptor (MOR) as a possible means for maintaining potent analgesis with reduced side effect profiles. While approaches measuring in vitro biased agonism are used in the development of these compounds, their therapeutic utility will ultimately...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312292/ https://www.ncbi.nlm.nih.gov/pubmed/32503269 http://dx.doi.org/10.3390/ijms21113999 |