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M1 Macrophages Promote TRAIL Expression in Adipose Tissue-Derived Stem Cells, Which Suppresses Colitis-Associated Colon Cancer by Increasing Apoptosis of CD133(+) Cancer Stem Cells and Decreasing M2 Macrophage Population

We have previously reported that adipose tissue-derived stem cells (ASCs) cultured at high cell density can induce cancer cell death through the expression of type I interferons and tumor necrosis factor (TNF)-related apoptosis-inducing ligands (TRAIL). Here, we investigated whether TRAIL-expressing...

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Detalles Bibliográficos
Autores principales: Eom, Young Woo, Akter, Rokeya, Li, Wanlu, Lee, Suji, Hwang, Soonjae, Kim, Jiye, Cho, Mee-Yon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312348/
https://www.ncbi.nlm.nih.gov/pubmed/32485960
http://dx.doi.org/10.3390/ijms21113887