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The Effect of Substituted Benzene-Sulfonamides and Clinically Licensed Drugs on the Catalytic Activity of CynT2, a Carbonic Anhydrase Crucial for Escherichia coli Life Cycle

Proteins are relevant antimicrobial drug targets, and among them, enzymes represent a significant group, since most of them catalyze reactions essential for supporting the central metabolism, or are necessary for the pathogen vitality. Genomic exploration of pathogenic and non-pathogenic microorgani...

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Detalles Bibliográficos
Autores principales: Del Prete, Sonia, De Luca, Viviana, Bua, Silvia, Nocentini, Alessio, Carginale, Vincenzo, Supuran, Claudiu T., Capasso, Clemente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312386/
https://www.ncbi.nlm.nih.gov/pubmed/32545297
http://dx.doi.org/10.3390/ijms21114175