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Nevirapine Biotransformation Insights: An Integrated In Vitro Approach Unveils the Biocompetence and Glutathiolomic Profile of a Human Hepatocyte-Like Cell 3D Model

The need for competent in vitro liver models for toxicological assessment persists. The differentiation of stem cells into hepatocyte-like cells (HLC) has been adopted due to its human origin and availability. Our aim was to study the usefulness of an in vitro 3D model of mesenchymal stem cell-deriv...

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Detalles Bibliográficos
Autores principales: Cipriano, Madalena, Pinheiro, Pedro F, Sequeira, Catarina O, Rodrigues, Joana S, Oliveira, Nuno G, Antunes, Alexandra M M, Castro, Matilde, Marques, M Matilde, Pereira, Sofia A, Miranda, Joana P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312429/
https://www.ncbi.nlm.nih.gov/pubmed/32503263
http://dx.doi.org/10.3390/ijms21113998