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Molecular Basis of Ubiquitination Catalyzed by the Bacterial Transglutaminase MavC

The Legionella pneumophila effector MavC is a transglutaminase that carries out atypical ubiquitination of the host ubiquitin (Ub)‐conjugation enzyme UBE2N by catalyzing the formation of an isopeptide bond between Gln40(Ub) and Lys92(UBE2N), which leads to inhibition of signaling in the NF‐κB pathwa...

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Detalles Bibliográficos
Autores principales: Guan, Hongxin, Fu, Jiaqi, Yu, Ting, Wang, Zhao‐Xi, Gan, Ninghai, Huang, Yini, Perčulija, Vanja, Li, Yu, Luo, Zhao‐Qing, Ouyang, Songying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312448/
https://www.ncbi.nlm.nih.gov/pubmed/32596129
http://dx.doi.org/10.1002/advs.202000871