Cargando…

Molecular Basis of Ubiquitination Catalyzed by the Bacterial Transglutaminase MavC

The Legionella pneumophila effector MavC is a transglutaminase that carries out atypical ubiquitination of the host ubiquitin (Ub)‐conjugation enzyme UBE2N by catalyzing the formation of an isopeptide bond between Gln40(Ub) and Lys92(UBE2N), which leads to inhibition of signaling in the NF‐κB pathwa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guan, Hongxin, Fu, Jiaqi, Yu, Ting, Wang, Zhao‐Xi, Gan, Ninghai, Huang, Yini, Perčulija, Vanja, Li, Yu, Luo, Zhao‐Qing, Ouyang, Songying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312448/ https://www.ncbi.nlm.nih.gov/pubmed/32596129 http://dx.doi.org/10.1002/advs.202000871

Ejemplares similares

Legionella pneumophila inhibits immune signaling via MavC-mediated transglutaminase-induced ubiquitination of UBE2N
por: Gan, Ninghai, et al.
Publicado: (2018)

Structural insights into the mechanism and inhibition of transglutaminase-induced ubiquitination by the Legionella effector MavC
por: Mu, Yajuan, et al.
Publicado: (2020)

Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination
por: Puvar, Kedar, et al.
Publicado: (2020)

Diverse Roles of DEAD/DEAH-Box Helicases in Innate Immunity and Diseases
por: Perčulija, Vanja, et al.
Publicado: (2019)

Cryo-EM structures of the human PA200 and PA200-20S complex reveal regulation of proteasome gate opening and two PA200 apertures
por: Guan, Hongxin, et al.
Publicado: (2020)

Functional Features and Current Applications of the RNA‐Targeting Type VI CRISPR‐Cas Systems
por: Perčulija, Vanja, et al.
Publicado: (2021)

Structural insights into target DNA recognition and cleavage by the CRISPR-Cas12c1 system
por: Zhang, Bo, et al.
Publicado: (2022)

Structural basis of AimP signaling molecule recognition by AimR in Spbeta group of bacteriophages
por: Zhen, Xiangkai, et al.
Publicado: (2018)

RNF115 plays dual roles in innate antiviral responses by catalyzing distinct ubiquitination of MAVS and MITA
por: Zhang, Zhi-Dong, et al.
Publicado: (2020)

Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1
por: Zhang, Bo, et al.
Publicado: (2021)

Regulation of phosphoribosyl ubiquitination by a calmodulin-dependent glutamylase
por: Gan, Ninghai, et al.
Publicado: (2019)

Structural and functional insights into a novel two-component endolysin encoded by a single gene in Enterococcus faecalis phage
por: Zhou, Biao, et al.
Publicado: (2020)

High-throughput sequencing and analysis of microbial communities in the mangrove swamps along the coast of Beibu Gulf in Guangxi, China
por: Gong, Bin, et al.
Publicado: (2019)

Molecular Basis of BioJ, a Unique Gatekeeper in Bacterial Biotin Synthesis
por: Wei, Wenhui, et al.
Publicado: (2019)

Structural basis for the prion-like MAVS filaments in antiviral innate immunity
por: Xu, Hui, et al.
Publicado: (2014)

Correction: Structural basis for the prion-like MAVS filaments in antiviral innate immunity
por: Xu, Hui, et al.
Publicado: (2015)

Transglutaminase-Catalyzed Bottom-Up Synthesis of Polymer Hydrogel
por: Lai, Enping, et al.
Publicado: (2022)

Interplay between bacterial deubiquitinase and ubiquitin E3 ligase regulates ubiquitin dynamics on Legionella phagosomes
por: Liu, Shuxin, et al.
Publicado: (2020)

MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades
por: Liu, Siqi, et al.
Publicado: (2013)

The mitochondrial ubiquitin ligase MARCH5 resolves MAVS aggregates during antiviral signalling
por: Yoo, Young-Suk, et al.
Publicado: (2015)

Structural basis for the RING catalyzed synthesis of K63 linked ubiquitin chains
por: Branigan, Emma, et al.
Publicado: (2015)

The MAVS and MAV-Nots: PINK1 Clears Prion-like MAVS Aggregates to Extinguish Mitochondrial Inflammatory Signaling
por: Rai, Prashant, et al.
Publicado: (2021)

Two HEPN domains dictate CRISPR RNA maturation and target cleavage in Cas13d
por: Zhang, Bo, et al.
Publicado: (2019)

Novel insights into stress-induced susceptibility to influenza: corticosterone impacts interferon-β responses by Mfn2-mediated ubiquitin degradation of MAVS
por: Luo, Zhuo, et al.
Publicado: (2020)

Tankyrases inhibit innate antiviral response by PARylating VISA/MAVS and priming it for RNF146-mediated ubiquitination and degradation
por: Xu, Yan-Ran, et al.
Publicado: (2022)

Insights into catalysis and function of phosphoribosyl-linked serine ubiquitination
por: Kalayil, Sissy, et al.
Publicado: (2018)

MAVS maintains mitochondrial homeostasis via autophagy
por: Sun, Xiaofeng, et al.
Publicado: (2016)

Estado de resultados MAV /
por: Martínez-Vera, Rubén
Publicado: (1986)

Transglutaminase-Catalyzed Glycosylation Improved Physicochemical and Functional Properties of Lentinus edodes Protein Fraction
por: Wu, Shan-shan, et al.
Publicado: (2023)

Structural Basis for Antigen Recognition by Transglutaminase 2-specific Autoantibodies in Celiac Disease
por: Chen, Xi, et al.
Publicado: (2015)

The E3 Ubiquitin Ligase Triad3A Negatively Regulates the RIG-I/MAVS Signaling Pathway by Targeting TRAF3 for Degradation
por: Nakhaei, Peyman, et al.
Publicado: (2009)

Rhodium-catalyzed reductive carbonylation of aryl iodides to arylaldehydes with syngas
por: Liu, Zhenghui, et al.
Publicado: (2020)

MAVS is a double-edged sword
por: Huang, Christina, et al.
Publicado: (2023)

MAVS-Mediated Apoptosis and Its Inhibition by Viral Proteins
por: Lei, Yu, et al.
Publicado: (2009)

Regulation of cGAS‐Mediated Immune Responses and Immunotherapy
por: Saeed, Abdullah F. U. H., et al.
Publicado: (2020)

Transglutaminase-catalyzed matrix cross-linking in differentiating cartilage: identification of osteonectin as a major glutaminyl substrate
Publicado: (1995)

Specific fluorescent labeling of chicken myofibril Z-line proteins catalyzed by guinea pig liver transglutaminase
Publicado: (1979)

Crosslinked Recombinant-Ara h 1 Catalyzed by Microbial Transglutaminase: Preparation, Structural Characterization and Allergic Assessment
por: Tian, Yang, et al.
Publicado: (2020)

Identification of Tyrosine-9 of MAVS as Critical Target for Inducible Phosphorylation That Determines Activation
por: Wen, Chaoyang, et al.
Publicado: (2012)

Magnesocenophane‐Catalyzed Amine Borane Dehydrocoupling
por: Wirtz, Lisa, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ihv0u4qdjo2kifppag72caco6k