Stable Fibroblast Growth Factor 2 Dimers with High Pro-Survival and Mitogenic Potential

Fibroblast growth factor 2 (FGF2) is a heparin-binding growth factor with broad mitogenic and cell survival activities. Its effector functions are induced upon the formation of 2:2 FGF2:FGFR1 tetrameric complex. To facilitate receptor activation, and therefore, to improve the FGF2 biological propert...

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Detalles Bibliográficos
Autores principales: Nawrocka, Daria, Krzyscik, Mateusz Adam, Opaliński, Łukasz, Zakrzewska, Malgorzata, Otlewski, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312490/
https://www.ncbi.nlm.nih.gov/pubmed/32526859
http://dx.doi.org/10.3390/ijms21114108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312490/
https://www.ncbi.nlm.nih.gov/pubmed/32526859
http://dx.doi.org/10.3390/ijms21114108

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