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Targeting of Intracellular TMEM16 Proteins to the Plasma Membrane and Activation by Purinergic Signaling

Anoctamins such as TMEM16A and TMEM16B are Ca(2+)-dependent Cl(−) channels activated through purinergic receptor signaling. TMEM16A (ANO1), TMEM16B (ANO2) and TMEM16F (ANO6) are predominantly expressed at the plasma membrane and are therefore well accessible for functional studies. While TMEM16A and...

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Detalles Bibliográficos
Autores principales: Schreiber, Rainer, Ousingsawat, Jiraporn, Kunzelmann, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312528/
https://www.ncbi.nlm.nih.gov/pubmed/32517157
http://dx.doi.org/10.3390/ijms21114065