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Targeting of Intracellular TMEM16 Proteins to the Plasma Membrane and Activation by Purinergic Signaling
Anoctamins such as TMEM16A and TMEM16B are Ca(2+)-dependent Cl(−) channels activated through purinergic receptor signaling. TMEM16A (ANO1), TMEM16B (ANO2) and TMEM16F (ANO6) are predominantly expressed at the plasma membrane and are therefore well accessible for functional studies. While TMEM16A and...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312528/ https://www.ncbi.nlm.nih.gov/pubmed/32517157 http://dx.doi.org/10.3390/ijms21114065 |