Homology Modeling of the Human P-glycoprotein (ABCB1) and Insights into Ligand Binding through Molecular Docking Studies

The ABCB1 transporter also known as P-glycoprotein (P-gp) is a transmembrane protein belonging to the ATP binding cassette super-family of transporters; it is a xenobiotic efflux pump that limits intracellular drug accumulation by pumping the compounds out of cells. P-gp contributes to a decrease of...

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Detalles Bibliográficos
Autores principales: Mora Lagares, Liadys, Minovski, Nikola, Caballero Alfonso, Ana Yisel, Benfenati, Emilio, Wellens, Sara, Culot, Maxime, Gosselet, Fabien, Novič, Marjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312539/
https://www.ncbi.nlm.nih.gov/pubmed/32517082
http://dx.doi.org/10.3390/ijms21114058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312539/
https://www.ncbi.nlm.nih.gov/pubmed/32517082
http://dx.doi.org/10.3390/ijms21114058

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