Identification of Selective Novel Hits against Plasmodium falciparum Prolyl tRNA Synthetase Active Site and a Predicted Allosteric Site Using In Silico Approaches

Recently, there has been increased interest in aminoacyl tRNA synthetases (aaRSs) as potential malarial drug targets. These enzymes play a key role in protein translation by the addition of amino acids to their cognate tRNA. The aaRSs are present in all Plasmodium life cycle stages, and thus present...

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Detalles Bibliográficos
Autores principales: Nyamai, Dorothy Wavinya, Tastan Bishop, Özlem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312540/
https://www.ncbi.nlm.nih.gov/pubmed/32471245
http://dx.doi.org/10.3390/ijms21113803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312540/
https://www.ncbi.nlm.nih.gov/pubmed/32471245
http://dx.doi.org/10.3390/ijms21113803

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