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Differentiation of Human Cardiac Atrial Appendage Stem Cells into Adult Cardiomyocytes: A Role for the Wnt Pathway?

Human cardiac stem cells isolated from atrial appendages based on aldehyde dehydrogenase activity (CASCs) can be expanded in vitro and differentiate into mature cardiomyocytes. In this study, we assess whether Wnt activation stimulates human CASC proliferation, whereas Wnt inhibition induces cardiac...

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Detalles Bibliográficos
Autores principales: Willems, Leen, Daniëls, Annick, Fanton, Yanick, Linsen, Loes, Evens, Lize, Bito, Virginie, Declercq, Jeroen, Rummens, Jean-Luc, Hensen, Karen, Hendrikx, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312541/
https://www.ncbi.nlm.nih.gov/pubmed/32486259
http://dx.doi.org/10.3390/ijms21113931