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High Homology-Directed Repair Using Mitosis Phase and Nucleus Localizing Signal

In homology-directed repair, mediated knock-in single-stranded oligodeoxynucleotides (ssODNs) can be used as a homologous template and present high efficiency, but there is still a need to improve efficiency. Previous studies have mainly focused on controlling double-stranded break size, ssODN stabi...

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Detalles Bibliográficos
Autores principales: Han, Jeong Pil, Chang, Yoo Jin, Song, Dong Woo, Choi, Beom Seok, Koo, Ok Jae, Yi, Seung Youn, Park, Tae Sub, Yeom, Su Cheong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312558/
https://www.ncbi.nlm.nih.gov/pubmed/32466470
http://dx.doi.org/10.3390/ijms21113747