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MnTBAP Reverses Pulmonary Vascular Remodeling and Improves Cardiac Function in Experimentally Induced Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH) is a life-threatening disease characterized by obstructed pulmonary vasculatures. Current therapies for PAH are limited and only alleviate symptoms. Reduced levels of BMPR2 are associated with PAH pathophysiology. Moreover, reactive oxygen species, inflammation...

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Detalles Bibliográficos
Autores principales: Gomez-Puerto, Maria Catalina, Sun, Xiao-Qing, Schalij, Ingrid, Orriols, Mar, Pan, Xiaoke, Szulcek, Robert, Goumans, Marie-José, Bogaard, Harm-Jan, Zhou, Qian, ten Dijke, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312610/
https://www.ncbi.nlm.nih.gov/pubmed/32531895
http://dx.doi.org/10.3390/ijms21114130