IGF-1 Deficiency Rescue and Intracellular Calcium Blockade Improves Survival and Corresponding Mechanisms in a Mouse Model of Acute Kidney Injury

This study was undertaken to test two therapies for acute kidney injury (AKI) prevention, IGF-1, which is renal protective, and BTP-2, which is a calcium entry (SOCE) inhibitor. We utilized lipopolysaccharide (LPS) IP, as a systemic model of AKI and studied in five groups of animals. Three experimen...

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Detalles Bibliográficos
Autores principales: Wasnik, Samiksha, Tang, Xiaolei, Bi, Hongzheng, Abdipour, Amir, E. Carreon, Edmundo, Sutjiadi, Brian, Lyu, Justin, Zhang, Jintao, Wilson, Sean, Baylink, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312627/
https://www.ncbi.nlm.nih.gov/pubmed/32521790
http://dx.doi.org/10.3390/ijms21114095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312627/
https://www.ncbi.nlm.nih.gov/pubmed/32521790
http://dx.doi.org/10.3390/ijms21114095

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