Albendazole-Induced SIRT3 Upregulation Protects Human Leukemia K562 Cells from the Cytotoxicity of MCL1 Suppression

Previous studies have shown that MCL1 stabilization confers cancer cells resistance to microtubule targeting agents (MTAs) and functionally extends the lifespan of MTA-triggered mitotically arrested cells. Albendazole (ABZ), a benzimidazole anthelmintic, shows microtubule-destabilizing activity and...

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Detalles Bibliográficos
Autores principales: Wang, Liang-Jun, Liou, Li-Ren, Shi, Yi-Jun, Chiou, Jing-Ting, Lee, Yuan-Chin, Huang, Chia-Hui, Huang, Po-Wei, Chang, Long-Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312678/
https://www.ncbi.nlm.nih.gov/pubmed/32486166
http://dx.doi.org/10.3390/ijms21113907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312678/
https://www.ncbi.nlm.nih.gov/pubmed/32486166
http://dx.doi.org/10.3390/ijms21113907

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