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Albendazole-Induced SIRT3 Upregulation Protects Human Leukemia K562 Cells from the Cytotoxicity of MCL1 Suppression
Previous studies have shown that MCL1 stabilization confers cancer cells resistance to microtubule targeting agents (MTAs) and functionally extends the lifespan of MTA-triggered mitotically arrested cells. Albendazole (ABZ), a benzimidazole anthelmintic, shows microtubule-destabilizing activity and...
Autores principales: | Wang, Liang-Jun, Liou, Li-Ren, Shi, Yi-Jun, Chiou, Jing-Ting, Lee, Yuan-Chin, Huang, Chia-Hui, Huang, Po-Wei, Chang, Long-Sen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312678/ https://www.ncbi.nlm.nih.gov/pubmed/32486166 http://dx.doi.org/10.3390/ijms21113907 |
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