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Hydrophobic Amino Acids as Universal Elements of Protein-Induced DNA Structure Deformation

Interaction with the DNA minor groove is a significant contributor to specific sequence recognition in selected families of DNA-binding proteins. Based on a statistical analysis of 3D structures of protein–DNA complexes, we propose that distortion of the DNA minor groove resulting from interactions...

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Detalles Bibliográficos
Autores principales: Faltejsková, Kateřina, Jakubec, David, Vondrášek, Jiří
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312683/
https://www.ncbi.nlm.nih.gov/pubmed/32498246
http://dx.doi.org/10.3390/ijms21113986