The Dual-Active Histamine H(3) Receptor Antagonist and Acetylcholine Esterase Inhibitor E100 Alleviates Autistic-Like Behaviors and Oxidative Stress in Valproic Acid Induced Autism in Mice

The histamine H3 receptor (H3R) functions as auto- and hetero-receptors, regulating the release of brain histamine (HA) and acetylcholine (ACh), respectively. The enzyme acetylcholine esterase (AChE) is involved in the metabolism of brain ACh. Both brain HA and ACh are implicated in several cognitiv...

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Detalles Bibliográficos
Autores principales: Eissa, Nermin, Azimullah, Sheikh, Jayaprakash, Petrilla, Jayaraj, Richard L., Reiner, David, Ojha, Shreesh K., Beiram, Rami, Stark, Holger, Łażewska, Dorota, Kieć-Kononowicz, Katarzyna, Sadek, Bassem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312782/
https://www.ncbi.nlm.nih.gov/pubmed/32503208
http://dx.doi.org/10.3390/ijms21113996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312782/
https://www.ncbi.nlm.nih.gov/pubmed/32503208
http://dx.doi.org/10.3390/ijms21113996

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