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p53-PHLDA3-Akt Network: The Key Regulators of Neuroendocrine Tumorigenesis

p53 is a well-known tumor suppressor gene and one of the most extensively studied genes in cancer research. p53 functions largely as a transcription factor and can trigger a variety of antiproliferative programs via induction of its target genes. We identified PHLDA3 as a p53 target gene and found t...

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Detalles Bibliográficos
Autores principales: Chen, Yu, Ohki, Rieko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312810/
https://www.ncbi.nlm.nih.gov/pubmed/32521808
http://dx.doi.org/10.3390/ijms21114098