Diseases Associated with Defects in tRNA CCA Addition

tRNA nucleotidyl transferase 1 (TRNT1) is an essential enzyme catalyzing the addition of terminal cytosine-cytosine-adenosine (CCA) trinucleotides to all mature tRNAs, which is necessary for aminoacylation. It was recently discovered that partial loss-of-function mutations in TRNT1 are associated wi...

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Detalles Bibliográficos
Autores principales: Slade, Angelo, Kattini, Ribal, Campbell, Chloe, Holcik, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312816/
https://www.ncbi.nlm.nih.gov/pubmed/32471101
http://dx.doi.org/10.3390/ijms21113780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312816/
https://www.ncbi.nlm.nih.gov/pubmed/32471101
http://dx.doi.org/10.3390/ijms21113780

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