β-Naphthoflavone and Ethanol Reverse Mitochondrial Dysfunction in A Parkinsonian Model of Neurodegeneration

The 1-methyl-4-phenylpyridinium (MPP(+)) is a parkinsonian-inducing toxin that promotes neurodegeneration of dopaminergic cells by directly targeting complex I of mitochondria. Recently, it was reported that some Cytochrome P450 (CYP) isoforms, such as CYP 2D6 or 2E1, may be involved in the developm...

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Detalles Bibliográficos
Autores principales: Fernandez-Abascal, Jesus, Chiaino, Elda, Frosini, Maria, Davey, Gavin P., Valoti, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312836/
https://www.ncbi.nlm.nih.gov/pubmed/32486438
http://dx.doi.org/10.3390/ijms21113955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312836/
https://www.ncbi.nlm.nih.gov/pubmed/32486438
http://dx.doi.org/10.3390/ijms21113955

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