Bioinformatics Analyses of the Transcriptome Reveal Ube3a-Dependent Effects on Mitochondrial-Related Pathways

The UBE3A gene encodes the ubiquitin E3-ligase protein, UBE3A, which is implicated in severe neurodevelopmental disorders. Lack of UBE3A expression results in Angelman syndrome, while UBE3A overexpression, due to genomic 15q duplication, results in autism. The cellular roles of UBE3A are not fully u...

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Detalles Bibliográficos
Autores principales: Panov, Julia, Simchi, Lilach, Feuermann, Yonatan, Kaphzan, Hanoch
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312912/
https://www.ncbi.nlm.nih.gov/pubmed/32532103
http://dx.doi.org/10.3390/ijms21114156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312912/
https://www.ncbi.nlm.nih.gov/pubmed/32532103
http://dx.doi.org/10.3390/ijms21114156

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