Sodium Glucose Co-Transporter 2 Inhibitor Ameliorates Autophagic Flux Impairment on Renal Proximal Tubular Cells in Obesity Mice

Obesity is supposed to cause renal injury via autophagy deficiency. Recently, sodium glucose co-transporter 2 inhibitors (SGLT2i) were reported to protect renal injury. However, the mechanisms of SGLT2i for renal protection are unclear. Here, we investigated the effect of SGLT2i for autophagy in ren...

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Detalles Bibliográficos
Autores principales: Fukushima, Kazuhiko, Kitamura, Shinji, Tsuji, Kenji, Sang, Yizhen, Wada, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312919/
https://www.ncbi.nlm.nih.gov/pubmed/32517059
http://dx.doi.org/10.3390/ijms21114054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312919/
https://www.ncbi.nlm.nih.gov/pubmed/32517059
http://dx.doi.org/10.3390/ijms21114054

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