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Imprinting of Mesenchymal Stromal Cell Transcriptome Persists even after Treatment in Patients with Multiple Myeloma

Introduction. Multiple myeloma (MM) is a B-cell neoplasm characterized by clonal expansion of malignant plasma cells (MM cells) in the bone-marrow (BM) compartment. BM mesenchymal stromal cells (MSC) from newly diagnosed MM patients were shown to be involved in MM pathogenesis and chemoresistance. T...

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Detalles Bibliográficos
Autores principales: Lemaitre, Léa, Do Souto Ferreira, Laura, Joubert, Marie-Véronique, Avet-Loiseau, Hervé, Martinet, Ludovic, Corre, Jill, Couderc, Bettina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312921/
https://www.ncbi.nlm.nih.gov/pubmed/32481768
http://dx.doi.org/10.3390/ijms21113854