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Permeation of Molecules through Astroglial Connexin 43 Hemichannels Is Modulated by Cytokines with Parameters Depending on the Permeant Species

Recent studies indicate that connexin hemichannels do not act as freely permeable non-selective pores, but they select permeants in an isoform-specific manner with cooperative, competitive and saturable kinetics. The aim of this study was to investigate whether the treatment with a mixture of IL-1β...

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Detalles Bibliográficos
Autores principales: Sáez, Juan C., Vargas, Aníbal A., Hernández, Diego E., Ortiz, Fernando C., Giaume, Christian, Orellana, Juan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312936/
https://www.ncbi.nlm.nih.gov/pubmed/32492823
http://dx.doi.org/10.3390/ijms21113970