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Nicotinamide Mononucleotide Administration Prevents Experimental Diabetes-Induced Cognitive Impairment and Loss of Hippocampal Neurons

Diabetes predisposes to cognitive decline leading to dementia and is associated with decreased brain NAD(+) levels. This has triggered an intense interest in boosting nicotinamide adenine dinucleotide (NAD(+)) levels to prevent dementia. We tested if the administration of the precursor of NAD(+), ni...

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Detalles Bibliográficos
Autores principales: Chandrasekaran, Krish, Choi, Joungil, Arvas, Muhammed Ikbal, Salimian, Mohammad, Singh, Sujal, Xu, Su, Gullapalli, Rao P, Kristian, Tibor, Russell, James William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313029/
https://www.ncbi.nlm.nih.gov/pubmed/32466541
http://dx.doi.org/10.3390/ijms21113756