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Molecular Mechanism of HSF1-Upregulated ALDH2 by PKC in Ameliorating Pressure Overload-Induced Heart Failure in Mice

Evidences abound that HSF1 and ALDH2 are of cardioprotective effect, yet there is still no report on whether HSF1 can regulate ALDH2 to delay the occurrence of heart failure. We first established the pressure overload-induced heart failure model of mice by transverse aortic constriction (TAC) and di...

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Detalles Bibliográficos
Autores principales: Ji, Endong, Jiao, Tiantian, Shen, Yunli, Xu, Yunjia, Sun, Yuanqing, Cai, Zichun, Zhang, Qi, Li, Jiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313111/
https://www.ncbi.nlm.nih.gov/pubmed/32626739
http://dx.doi.org/10.1155/2020/3481623