Cargando…

Molecular Mechanism of HSF1-Upregulated ALDH2 by PKC in Ameliorating Pressure Overload-Induced Heart Failure in Mice

Evidences abound that HSF1 and ALDH2 are of cardioprotective effect, yet there is still no report on whether HSF1 can regulate ALDH2 to delay the occurrence of heart failure. We first established the pressure overload-induced heart failure model of mice by transverse aortic constriction (TAC) and di...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ji, Endong, Jiao, Tiantian, Shen, Yunli, Xu, Yunjia, Sun, Yuanqing, Cai, Zichun, Zhang, Qi, Li, Jiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313111/ https://www.ncbi.nlm.nih.gov/pubmed/32626739 http://dx.doi.org/10.1155/2020/3481623

Ejemplares similares

Downregulation of MiR-199b-5p Inducing Differentiation of Bone-Marrow Mesenchymal Stem Cells (BMSCs) Toward Cardiomyocyte-Like Cells via HSF1/HSP70 Pathway
por: Dai, Fangjie, et al.
Publicado: (2018)

Axitinib targets cardiac fibrosis in pressure overload-induced heart failure through VEGFA-KDR pathway
por: Jiao, Tiantian, et al.
Publicado: (2023)

Mitochondrial division/mitophagy inhibitor (Mdivi) Ameliorates Pressure Overload Induced Heart Failure
por: Givvimani, Srikanth, et al.
Publicado: (2012)

Tonantzitlolone cytotoxicity toward renal cancer cells is PKCθ- and HSF1-dependent
por: Sourbier, Carole, et al.
Publicado: (2015)

Alpha-lipoic acid protects against pressure overload-induced heart failure via ALDH2-dependent Nrf1-FUNDC1 signaling
por: Li, Wenjia, et al.
Publicado: (2020)

PKC-ALDH2 Pathway Plays a Novel Role in Adipocyte Differentiation
por: Yu, Yu-Hsiang, et al.
Publicado: (2016)

The Overexpression of Twinkle Helicase Ameliorates the Progression of Cardiac Fibrosis and Heart Failure in Pressure Overload Model in Mice
por: Tanaka, Atsushi, et al.
Publicado: (2013)

The urotensin II receptor antagonist DS37001789 ameliorates mortality in pressure-overload mice with heart failure
por: Nishi, Mina, et al.
Publicado: (2020)

Upregulation of HSF1 in estrogen receptor positive breast cancer
por: Gökmen-Polar, Yesim, et al.
Publicado: (2016)

Hydrogen Sulfide Ameliorates Homocysteine-Induced Cognitive Dysfunction by Inhibition of Reactive Aldehydes Involving Upregulation of ALDH2
por: Li, Min, et al.
Publicado: (2016)

Activation of PKCε-ALDH2 Axis Prevents 4-HNE-Induced Pain in Mice
por: Martins, Bárbara B., et al.
Publicado: (2021)

Right Ventricular Dysfunction and Failure in Chronic Pressure Overload
por: Simon, Marc A., et al.
Publicado: (2011)

Upregulation of ALDH1B1 promotes tumor progression in osteosarcoma
por: Wang, Xin, et al.
Publicado: (2017)

Rutaecarpine Ameliorates Pressure Overload Cardiac Hypertrophy by Suppression of Calcineurin and Angiotensin II
por: Li, Shujun, et al.
Publicado: (2021)

Alpha-ketoglutarate ameliorates pressure overload-induced chronic cardiac dysfunction in mice
por: An, Dongqi, et al.
Publicado: (2021)

Hsp70 and HSF-1 expression is altered in the tissues of pigs transported for various periods of times
por: Zhang, Miao, et al.
Publicado: (2012)

Rescue of Pressure Overload‐Induced Heart Failure by Estrogen Therapy
por: Iorga, Andrea, et al.
Publicado: (2016)

Pressure Overload and Right Ventricular Failure: From Pathophysiology to Treatment
por: Dayer, Nicolas, et al.
Publicado: (2023)

Trimetazidine enhances myocardial angiogenesis in pressure overload-induced cardiac hypertrophy mice through directly activating Akt and promoting the binding of HSF1 to VEGF-A promoter
por: Shu, Hong-yang, et al.
Publicado: (2022)

Anti-Parstatin Promotes Angiogenesis and Ameliorates Left Ventricular Dysfunction during Pressure Overload
por: Givvimani, Srikanth, et al.
Publicado: (2014)

Mitoquinone ameliorates pressure overload-induced cardiac fibrosis and left ventricular dysfunction in mice
por: Goh, Kah Yong, et al.
Publicado: (2019)

TRPA1 inhibition ameliorates pressure overload-induced cardiac hypertrophy and fibrosis in mice
por: Wang, Zhen, et al.
Publicado: (2018)

Sacubitril/valsartan ameliorates cardiac hypertrophy and preserves diastolic function in cardiac pressure overload
por: Nordén, Einar Sjaastad, et al.
Publicado: (2021)

Thymoquinone ameliorates pressure overload‐induced cardiac hypertrophy by activating the AMPK signalling pathway
por: Chen, Heng, et al.
Publicado: (2021)

Protective effect of resveratrol against pressure overload-induced heart failure
por: Gupta, Prakash K, et al.
Publicado: (2014)

T cell costimulation blockade blunts pressure overload-induced heart failure
por: Kallikourdis, Marinos, et al.
Publicado: (2017)

Effects of 6-mercaptopurine in pressure overload induced right heart failure
por: Axelsen, Julie Birkmose, et al.
Publicado: (2019)

Regulation and impact of cardiac lymphangiogenesis in pressure-overload-induced heart failure
por: Heron, Coraline, et al.
Publicado: (2022)

miR-21 upregulation exacerbates pressure overload-induced cardiac hypertrophy in aged hearts
por: Chang, Wei-Ting, et al.
Publicado: (2022)

Aberrant HSF1 signaling activation underlies metformin amelioration of myocardial infarction in mice
por: Wang, Mingyuan, et al.
Publicado: (2022)

Sildenafil ameliorates right ventricular early molecular derangement during left ventricular pressure overload
por: Imai, Yousuke, et al.
Publicado: (2018)

Cellular hypertrophy occurs before interstitial fibrosis in pressure-overload heart failure
por: Shah, Ravi, et al.
Publicado: (2013)

Mononuclear Phagocytes Are Dispensable for Cardiac Remodeling in Established Pressure-Overload Heart Failure
por: Patel, Bindiya, et al.
Publicado: (2017)

MitoQ improves mitochondrial dysfunction in heart failure induced by pressure overload
por: Ribeiro Junior, Rogério Faustino, et al.
Publicado: (2018)

Inhibition of PKC-dependent extracellular Ca(2+) entry contributes to the depression of contractile activity in long-term pressure-overloaded endothelium-denuded rat aortas
por: Padilla, J., et al.
Publicado: (2014)

ALDEFLUOR activity, ALDH isoforms, and their clinical significance in cancers
por: Duan, Jiang-Jie, et al.
Publicado: (2023)

HSF1 and HSF3 cooperatively regulate the heat shock response in lizards
por: Takii, Ryosuke, et al.
Publicado: (2017)

Low-intensity pulsed ultrasound enhances angiogenesis and ameliorates contractile dysfunction of pressure-overloaded heart in mice
por: Ogata, Tsuyoshi, et al.
Publicado: (2017)

Inhibition of Interleukin‐6/glycoprotein 130 signalling by Bazedoxifene ameliorates cardiac remodelling in pressure overload mice
por: Shi, Wei, et al.
Publicado: (2020)

Ameliorated ConA-Induced Hepatitis in the Absence of PKC-theta
por: Fang, Xianfeng, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_dsbrj5uj12crsak076a0mrgh0f