High expression of AMAP1, an ARF6 effector, is associated with elevated levels of PD-L1 and fibrosis of pancreatic cancer

BACKGROUND: Not merely the onset of immune evasion, but other factors, such as acidosis and fibrosis, are also major barriers in cancer therapeutics. Dense fibrosis is a hallmark of pancreatic ductal carcinoma (PDAC), in which hyperactivation of focal adhesion kinase (FAK) in tumor cells was shown t...

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Detalles Bibliográficos
Autores principales: Tsutaho, Akio, Hashimoto, Ari, Hashimoto, Shigeru, Hata, Soichiro, Kachi, Shion, Hirano, Satoshi, Sabe, Hisataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313132/
https://www.ncbi.nlm.nih.gov/pubmed/32580737
http://dx.doi.org/10.1186/s12964-020-00608-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313132/
https://www.ncbi.nlm.nih.gov/pubmed/32580737
http://dx.doi.org/10.1186/s12964-020-00608-8

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