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Implications of HIF-1α in the tumorigenesis and progression of pancreatic cancer

Pancreatic cancer is one of the leading causes of cancer-related deaths worldwide and is characterized by highly hypoxic tumor microenvironment. Hypoxia-inducible factor-1 alpha (HIF-1α) is a major regulator of cellular response to changes in oxygen concentration, supporting the adaptation of tumor...

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Detalles Bibliográficos
Autores principales: Jin, Xiao, Dai, Lu, Ma, Yilan, Wang, Jiayan, Liu, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313137/
https://www.ncbi.nlm.nih.gov/pubmed/32587480
http://dx.doi.org/10.1186/s12935-020-01370-0